The primary interest of our research team is the restoration of respiratory muscle function in individuals with spinal cord injury. This research emphasizes the role of feedback, muscle mechanical properties of the limbs in the execution and regulation of movements. Current research projects include the control of wrist flexion/extension and elbow extension in patients with…
My major research interests are in the area of movement control and regulation of posture, particularly the restoration of movement by neuroprostheses employing neuromuscular stimulation. This research emphasizes the role of feedback, muscle mechanical properties of the limbs in the execution and regulation of movements. Current research projects include the control of wrist flexion/extension and…
Areas of Interest Geriatric Psychiatry Publications (Select) Entire publication list can be found here. Publications Chen P, Guarino PD, Dysken MW, Pallaki M, Asthana S, Llorente MD, Love S, Vertrees JE, Schellenberg GD, Sano M. Neuropsychiatric Symptoms and Caregiver Burden in Individuals With Alzheimer’s Disease: The TEAM-AD VA Cooperative Study. J Geriatr Psychiatry Neurol. 2018 Jul;31(4):177–185. doi: 10.1177/0891988718783897 Pubmed…
My research interests are in the areas of post-stroke, upper and lower limb motor and functional restoration, and shoulder pain in hemiplegia. Active Projects Various forms of electrical stimulation for upper limb motor relearningPeroneal nerve stimulation for motor relearning and neuroprosthetic effectsImplanted neuroprostheses for upper and lower limb motor restorationImplanted and surface stimulation for reduction…
My Lab is studying various aspects of microelectrode performance, and pursuing both materials-based and therapeutic-mediated methods to mitigate the inflammatory-mediated microelectrode failure mechanisms. My group has made significant contributions to this field, including our work describing the roles of oxidative stress, innate immunity pathways, tissue/device mechanical mismatch, device sterility (endotoxin contamination), and the contribution of…
Research interests include improvement of clinical outcomes in under-served populations of bipolar disorder, including those with rapid cycling, children and adolescents, adults currently abusing alcohol and/or drugs, forensic complications of bipolar disorder, those receiving care within community mental health centers, older adults, and members of the Ohio national guard and reserve. Publications (Select) Entire publication…
As an Occupational Therapist and Sociologist, Anne is deeply committed to improving the lives of people with spinal cord injury. With more than twenty years of experience specializing in upper extremity care of people with cervical spinal cord injury, Anne leads the functional assessment program for upper extremity neuroprosthetics and reconstructive surgeries at The Cleveland…
Spinal cord injury (SCI) has a devastating impact on quality of life. Many investigators, clinicians, and especially people with SCI identify bladder, bowel, and sexual functions as important targets for therapies. However, there remains a lack of available approaches for restoring these functions. To serve this unmet need, my research focuses on developing devices that…
My ongoing research is investigating high-frequency waveforms for inducing a rapid yet fully reversible peripheral motor nerve block, which will have clinical applications in the control of spasticity and other movement disorders. The various aspects of this research are; computer modeling to investigate the mechanism of high-frequency block, designing wave forms that will not produce…
Areas of Interest Design of neural stimulation electrodes for FES applicationsNeuroprostheses and Feedback control for Lower Urinary Tract RehabilitationAfferent based stimulus paradigmsNeuroprosthetic applications of High Frequency nerve block Publications (Select) Publications Bhadra N, Foldes E, Vrabec T, Kilgore K, Bhadra N. Temporary persistence of conduction block after prolonged kilohertz frequency alternating current on rat…