As an Occupational Therapist and Sociologist, Anne is deeply committed to improving the lives of people with spinal cord injury.

With more than twenty years of experience specializing in upper extremity care of people with cervical spinal cord injury, Anne leads the functional assessment program for upper extremity neuroprosthetics and reconstructive surgeries at The Cleveland FES Center. Currently she is responsible for leading the multi-center pivotal clinical trial for the Networked Neuroprosthesis (NNP) System, the latest innovation developed at the Cleveland FES Center. Her research interests include upper extremity assessment, surgical interventions, outcomes measurement, and the social determinants of health and wellness in people with chronic physical disability.

Additionally, Anne is investigating the experiences of health and social resource navigation following spinal cord injury through the lens of human rights by measuring barriers and facilitators to obtaining supports necessary for improved quality of life. She is also conducting research on the human rights knowledge base of health professionals and other stakeholders involved in the care of people with spinal cord injury.

Research Programs

  • Human Rights, Science, and Disability: Attitudes of Health Care Providers and Scientists, Science and Human Rights Coalition of the American Association for the Advancement of Science

Publications (Select)

Entire publication list can be found here.

Anderson KD, Bryden AM, Moynahan M. Risk-benefit value of upper extremity function by an implanted electrical stimulation device targeting chronic cervical spinal cord injury. Spinal Cord Ser Cases. 2019 Jul 24;5:68. doi: 10.1038/s41394-019-0213-9. PMID: 31632726; PMCID: PMC6786403.

Wilson RD, Bryden AM, Kilgore KL, Makowski N, Bourbeau D, Kowalski KE, DiMarco AF, Knutson JS. Neuromodulation for Functional Electrical Stimulation. Phys Med Rehabil Clin N Am. 2019 May;30(2):301-318. doi: 10.1016/j.pmr.2018.12.011. PMID: 30954149.

Kilgore KL, Bryden A, Keith MW, Hoyen HA, Hart RL, Nemunaitis GA, Peckham PH. Evolution of Neuroprosthetic Approaches to Restoration of Upper Extremity Function in Spinal Cord Injury. Top Spinal Cord Inj Rehabil. 2018 Summer;24(3):252-264. doi: 10.1310/sci2403-252. PMID: 29997428; PMCID: PMC6037324.

MRJ, Sinko R, Bryden A, Backus D, Chen D, Nemunaitis GA, Leiby BE. Comparison of Responsiveness and Minimal Clinically Important Difference of the Capabilities of Upper Extremity Test (CUE-T) and the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP). Top Spinal Cord Inj Rehabil. 2018 Summer;24(3):227-238. doi: 10.1310/sci2403-227. PMID: 29997426; PMCID:

Bryden A, Kilgore KL, Nemunaitis GA. Advanced Assessment of the Upper Limb in Tetraplegia: A Three-Tiered Approach to Characterizing Paralysis. Top Spinal Cord Inj Rehabil. 2018 Summer;24(3):206-216. doi: 10.1310/sci2403-206. PMID: 29997424; PMCID: PMC6037326.

Jones LAT, Bryden A, Wheeler TL, Tansey KE, Anderson KD, Beattie MS, Blight  A, Curt A, Field-Fote E, Guest JD, Hseih J, Jakeman LB, Kalsi-Ryan S, Krisa L, Lammertse DP, Leiby B, Marino R, Schwab JM, Scivoletto G, Tulsky DS, Wirth E, Zariffa J, Kleitman N, Mulcahey MJ, Steeves JD. Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials. Spinal Cord. 2018 May;56(5):414-425. doi: 10.1038/s41393-017-0015-5. Epub 2017 Dec 28. PMID: 29284795; PMCID: PMC5951792.

Hardwick D, Bryden A, Kubec G, Kilgore K. Factors associated with upper extremity contractures after cervical spinal cord injury: A pilot study. J Spinal Cord Med. 2018 May;41(3):337-346. doi: 10.1080/10790268.2017.1331894. Epub 2017 Jun 5. PMID: 28580861; PMCID: PMC6055953.

Peterson CL, Bednar MS, Bryden AM, Keith MW, Perreault EJ, Murray WM. Voluntary activation of biceps-to-triceps and deltoid-to-triceps transfers in quadriplegia. PLoS One. 2017 Mar 2;12(3):e0171141. doi: 10.1371/journal.pone.0171141. PMID: 28253262; PMCID: PMC5333805.

Peterson CL, Rogers LM, Bednar MS, Bryden AM, Keith MW, Perreault EJ, Murray WM. Posture-Dependent Corticomotor Excitability Differs Between the Transferred Biceps in Individuals With Tetraplegia and the Biceps of Nonimpaired Individuals. Neurorehabil Neural Repair. 2017 Apr;31(4):354-363. doi: 10.1177/1545968316680488. Epub 2016 Dec 8. PMID: 27932695; PMCID: PMC5364050.

Bryden AM, Hoyen HA, Keith MW, Mejia M, Kilgore KL, Nemunaitis GA. Upper Extremity Assessment in Tetraplegia: The Importance of Differentiating Between Upper and Lower Motor Neuron Paralysis. Arch Phys Med Rehabil. 2016 Jun;97(6 Suppl):S97-S104. doi: 10.1016/j.apmr.2015.11.021. PMID: 27233597.

Peterson CL, Rogers LM, Mogk JP, Bednar MS, Bryden AM, Keith MW, Perreault EJ, Murray WM. Posture-dependent changes in corticomotor excitability of the biceps after spinal cord injury and tendon transfer. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:4302-5. doi: 10.1109/EMBC.2014.6944576. PMID: 25570944.

Memberg WD, Polasek KH, Hart RL, Bryden AM, Kilgore KL, Nemunaitis GA, Hoyen HA, Keith MW, Kirsch RF. Implanted neuroprosthesis for restoring arm and hand function in people with high level tetraplegia. Arch Phys Med Rehabil. 2014 Jun;95(6):1201-1211.e1. doi: 10.1016/j.apmr.2014.01.028. Epub 2014 Feb 20. PMID: 24561055; PMCID: PMC4470503.

Knutson JS, Chae J, Hart RL, Keith MW, Hoyen HA, Harley MY, Hisel TZ, BrydenAM, Kilgore KL, Peckham H. Implanted neuroprosthesis for assisting arm and hand function after stroke: a case study. J Rehabil Res Dev. 2012;49(10):1505-16. doi: 10.1682/jrrd.2011.09.0171. PMID: 23516054; PMCID: PMC3605749.

Bryden AM, Ancans J, Mazurkiewicz J, McKnight A, Scholtens M. Technology for spinal cord injury rehabilitation and its application to youth. J Pediatr Rehabil Med. 2012;5(4):287-99. doi: 10.3233/PRM-2012-00227. PMID: 23411770.

Cornwell AS, Liao JY, Bryden AM, Kirsch RF. Standard task set for evaluating rehabilitation interventions for individuals with arm paralysis. J Rehabil Res Dev. 2012;49(3):395-403. doi: 10.1682/jrrd.2011.03.0040. PMID: 22773199; PMCID: PMC3700423.

Bryden A, Bezruczko N. An ADL measure for spinal cord injury. J Appl Meas. 2011;12(3):279-97. PMID: 22357128.

Bryden AM, Peljovich AE, Hoyen HA, Nemunaitis G, Kilgore KL, Keith MW. Surgical restoration of arm and hand function in people with tetraplegia. Top Spinal Cord Inj Rehabil. 2012 Winter;18(1):43-9. doi: 10.1310/sci180143. PMID: 23459698; PMCID: PMC3584747.

Dunn JA, Sinnott KA, Bryden AM, Connolly SJ, Rothwell AG. Measurement issues related to upper limb interventions in persons who have tetraplegia. Hand Clin. 2008 May;24(2):161-8, v. doi: 10.1016/j.hcl.2008.01.005. PMID: 18456122.

Kilgore KL, Hoyen HA, Bryden AM, Hart RL, Keith MW, Peckham PH. An implanted upper-extremity neuroprosthesis using myoelectric control. J Hand Surg Am. 2008 Apr;33(4):539-50. doi: 10.1016/j.jhsa.2008.01.007. PMID: 18406958; PMCID: PMC2743484.

Kilgore KL, Hart RL, Montague FW, Bryden AM, Keith MW, Hoyen HA, Sams CJ, Peckham PH. An implanted myoelectrically-controlled neuroprosthesis for upper extremity function in spinal cord injury. Conf Proc IEEE Eng Med Biol Soc. 2006;2006:1630-3. doi: 10.1109/IEMBS.2006.259939. PMID: 17946056.

Bryden AM, Kilgore KL, Lind BB, Yu DT. Triceps denervation as a predictor of elbow flexion contractures in C5 and C6 tetraplegia. Arch Phys Med Rehabil. 2004
Nov;85(11):1880-5. doi: 10.1016/j.apmr.2004.01.042. PMID: 15520985.

Kilgore KL, Peckham PH, Keith MW, Montague FW, Hart RL, Gazdik MM, Bryden AM, Snyder SA, Stage TG. Durability of implanted electrodes and leads in an upper-limb neuroprosthesis. J Rehabil Res Dev. 2003 Nov Dec;40(6):457-68. doi: 10.1682/jrrd.2003.11.0457. PMID: 15077658.

Wuolle KS, Bryden AM, Peckham PH, Murray PK, Keith M. Satisfaction with upper-extremity surgery in individuals with tetraplegia. Arch Phys Med Rehabil.2003 Aug;84(8):1145-9. doi: 10.1016/s0003-9993(03)00292-2. PMID: 12917852. 

Murray WM, Bryden AM, Kilgore KL, Keith MW. The influence of elbow position on the range of motion of the wrist following transfer of the brachioradialis to the extensor carpi radialis brevis tendon. J Bone Joint Surg Am. 2002 Dec;84(12):2203-10. doi: 10.2106/00004623-200212000-00012. PMID: 12473709.

Peckham PH, Kilgore KL, Keith MW, Bryden AM, Bhadra N, Montague FW. An advanced neuroprosthesis for restoration of hand and upper arm control using an implantable controller. J Hand Surg Am. 2002 Mar;27(2):265 76. doi: 10.1053/jhsu.2002.30919. PMID: 11901386.


Cleveland FES Center

Director, Clinical Trials and Research, Institute for Functional Restoration
Case Western Reserve University

Doctoral Candidate, Department of Sociology
Case Western Reserve University


Program Contact
Anne Bryden

Contact Number
(216) 957-3594

Contact Email