Restoration of walking in paralyzed persons using electronic orthotics Publications (Select) Entire publication list can be found here. Publications Osman SG, Schwartz JA, Marsolais EB. Arthroscopic discectomy and interbody fusion of the thoracic spine: A report of ipsilateral 2-portal approach. Int J Spine Surg. 2012 Dec 1;6:103-9. doi: 10.1016/j.ijsp.2012.02.004. eCollection 2012. PubMed PMID: 25694878; PubMed Central PMCID: PMC4300888. Daly JJ,…
My primary research interest is determining the contributions of post-stroke impairments to function and developing interventions for motor restoration after stroke. The present focus is on functional electrical stimulation (FES) to assist with gait. Areas of Interest Implanted FES systems for gait restoration after stroke.Determining the mechanisms that contribute to gait deficits and developing combinatorial…
Areas of Interest Quantitative image analysisMachine LearningTheragnosticsMagnetic resonance imaging (MRI)Cancer imagingBreast cancerProstate cancerArtificial IntelligenceDigital pathologyPsychiatry, mental/behavioral health Publications (Select) Entire publication list can be found here. Publications Peyster EG, Madabhushi A, Margulies KB. Advanced Morphologic Analysis for Diagnosing Allograft Rejection: The Case of Cardiac Transplant Rejection. Transplantation. 2018 Aug;102(8):1230-1239. doi: 10.1097/TP.0000000000002189. PubMed PMID: 29570167; PubMed Central PMCID: PMC6059998. Antunes J, Viswanath S, Brady…
Dr. Machado leads several deep brain stimulation and neuromodulation clinical trials as well as laboratory research. His research in deep brain stimulation for thalamic pain syndrome was awarded the National Institutes of Health Director’s New Innovator’s Award. In addition, he conducts deep brain stimulation research for treatment refractory depression as well as obsessive…
Dr. Lhatoo’s clinical and research interests are the investigation and management of refractory epilepsy; mortality of epilepsy with particular regard to sudden death in epilepsy (SUDEP) Publications (Select) Publications Jamal-Omidi S, Collins C, Fulchiero E, Liu H, Colon-Zimmermann K, Fuentes-Casiano E, Tatsuoka C, Cassidy KA, Lhatoo S, Sajatovic M. Assessing depression severity with a self-rated vs. rater-administered instrument in patients…
Areas of Interest Processing/structure/property relationships in ferrous and non-ferrous engineering materialsEffects of superposed pressure on deformation/fracture; fatigue and fracture of intermetallics and composites, bulk metallic glass, and layered/laminated materials Deformation processing; blast-resistant materials; advanced engineered materials systemsFracture and fatigue of biomedical materials; failure analysis; and additive manufacturing. Publications (Select) Entire publication list can be found…
The purpose of our studies is to restore respiratory muscle function in patients with spinal cord injury. We are developing systems for electrical activation of the inspiratory muscles to maintain full-time ventilatory support in patients with ventilator-dependent tetraplegia and electrical activation of the expiratory muscles to provide an effective cough mechanism in patients with expiratory…
My research centers on development and clinical trials of new interventions for training and restoring human function after neurologic injury. These interventions are the result of translating technologies from the areas of robotics, human-computer interfaces, and virtual environments. Research Programs Upper Extremity FES Program Publications (Select) Entire publication list can be found here. Publications Kilgore…
Areas of Interest NeurologyPsychiatry, mental/behavioral health Publications (Select) Publications Mahajan GJ, Vallender EJ, Garrett MR, Challagundla L, Overholser JC, Jurjus G, Dieter L, Syed M, Romero DG, Benghuzzi H, Stockmeier CA. Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Mar 2;82:177-186. doi: 10.1016/j.pnpbp.2017.11.017. Epub 2017 Nov 22. PubMed PMID: 29175309; PubMed Central PMCID: PMC5801125. Mohamed S,…
In recent years, it has been become clear that modulating the autonomic nervous system has great potential for treating diseases. Neuromodulation of the vagus nerve has shown potential to treat several diseases including rheumatoid arthritis, epilepsy, hypertension, obesity, heart failure, and coma. Neuromodulation devices potentially have several advantages over pharmaceuticals including reduced side effects and…