My primary areas of research focus on the development of minimally invasive neural interfaces for lower risk, lower cost, and higher impact applications in bioelectronic medicine and neural prostheses

Other areas of interest include neuroanatomy and physiology, biomaterials, drug delivery, and inflammation.   For more information, please visit

Publications (Select)

Entire publication list can be found here.

1: Settell ML, Pelot NA, Knudsen BE, Dingle AM, McConico AL, Nicolai EN,
Trevathan JK, Ezzell JA, Ross EK, Gustafson KJ, Shoffstall AJ, Williams JC, Zeng
W, Poore SO, Populin LC, Suminski AJ, Grill WM, Ludwig KA. Functional vagotopy in
the cervical vagus nerve of the domestic pig: implications for the study of vagus
nerve stimulation. J Neural Eng. 2020 Apr 9;17(2):026022. doi:
10.1088/1741-2552/ab7ad4. PubMed PMID: 32108590.

2: Trevathan JK, Baumgart IW, Nicolai EN, Gosink BA, Asp AJ, Settell ML,
Polaconda SR, Malerick KD, Brodnick SK, Zeng W, Knudsen BE, McConico AL, Sanger
Z, Lee JH, Aho JM, Suminski AJ, Ross EK, Lujan JL, Weber DJ, Williams JC, Franke
M, Ludwig KA, Shoffstall AJ. An Injectable Neural Stimulation Electrode Made from
an In-Body Curing Polymer/Metal Composite. Adv Healthc Mater. 2019
Dec;8(23):e1900892. doi: 10.1002/adhm.201900892. Epub 2019 Nov 7. PubMed PMID:

3: Capadona JR, Shoffstall AJ, Pancrazio JJ. Neuron-like neural probes. Nat
Mater. 2019 May;18(5):429-431. doi: 10.1038/s41563-019-0312-9. PubMed PMID:
30804508; PubMed Central PMCID: PMC6986371.

4: Lindner SC, Yu M, Capadona JR, Shoffstall AJ. A graphical user interface to
assess the neuroinflammatory response to intracortical microelectrodes. J
Neurosci Methods. 2019 Apr 1;317:141-148. doi: 10.1016/j.jneumeth.2019.01.003.
Epub 2019 Jan 18. PubMed PMID: 30664915; PubMed Central PMCID: PMC6914213.


Cleveland FES Center

Assistant Professor, Department of Biomedical Engineering
Case Western Reserve University

Research Associate
Louis Stokes Cleveland VA Medical Center


Program Contact
Andrew Shoffstall, PhD

Contact Email