Dr. Onders spent his early years at UH developing a minimally invasive procedure to allow ventilator-free breathing for paralyzed patients. 

More recently, Dr. Onders has led the effort to apply that same technology in patients with the progressive neurological disorder Amyotrophic Lateral Sclerosis (ALS).

Publications (Select)

Entire publication list can be found here.

  • Onders RP, Markowitz A, Ho VP, Hardacre J, Novitsky Y, Towe C, Elmo M, Kaplan C, Schilz R. Completed FDA feasibility trial of surgically placed temporary diaphragm pacing electrodes: A promising option to prevent and treat respiratory failure. Am J Surg. 2018 Mar;215(3):518–521. doi: 10.1016/j.amjsurg.2017.10.054 Pubmed PMID: 29195690
  • Smith BK, Fuller DD, Martin AD, Lottenberg L, Islam S, Lawson LA, Onders RP, Byrne BJ. Diaphragm Pacing as a Rehabilitative Tool for Patients With Pompe Disease Who Are Ventilator-Dependent: Case Series. Phys Ther. 2016 May;96(5):696-703. doi: 10.2522/ptj.20150122. Epub 2016 Feb 18. PubMed PMID: 26893511; PubMed Central PMCID: PMC4858660.
  • Onders RP, Elmo M, Kaplan C, Katirji B, Schilz R. Identification of unexpected respiratory abnormalities in patients with amyotrophic lateral sclerosis through electromyographic analysis using intramuscular electrodes implanted for therapeutic diaphragmatic pacing. Am J Surg. 2015 Mar;209(3):451-6. doi: 10.1016/j.amjsurg.2014.10.008. Epub 2014 Dec 11. PubMed PMID: 25648901.
  • Onders RP. The diaphragm: how it affected my career and my life. The search for stability when the problem is instability. Am J Surg. 2014 Dec 18. pii: S0002-9610(14)00620-5. doi: 10.1016/j.amjsurg.2014.12.003. [Epub ahead of print] PubMed PMID: 25637310.
  • Onders RP, Elmo M, Kaplan C, Katirji B, Schilz R. Identification of unexpected respiratory abnormalities in patients with amyotrophic lateral sclerosis through electromyographic analysis using intramuscular electrodes implanted for therapeutic diaphragmatic pacing. Am J Surg. 2014 Dec 11. pii: S0002-9610(14)00598-4. doi: 10.1016/j.amjsurg.2014.10.008. [Epub ahead of print] PubMed PMID: 25648901.
  • Onders RP, Elmo M, Kaplan C, Katirji B, Schilz R. Final analysis of the pilot trial of diaphragm pacing in amyotrophic lateral sclerosis with long-term follow-up: diaphragm pacing positively affects diaphragm respiration. Am J Surg. 2014 Mar;207(3):393-7; discussion 397. doi: 10.1016/j.amjsurg.2013.08.039. Epub 2013 Dec 19. PubMed PMID: 24439161.
  • Posluszny JA Jr, Onders R, Kerwin AJ, Weinstein MS, Stein DM, Knight J, Lottenberg L, Cheatham ML, Khansarinia S, Dayal S, Byers PM, Diebel L. Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration. J Trauma Acute Care Surg. 2014 Feb;76(2):303-9; discussion 309-10. doi: 10.1097/TA.0000000000000112. PubMed PMID: 24458038.
  • Marks JM, Phillips MS, Tacchino R, Roberts K, Onders R, DeNoto G, Gecelter G, Rubach E, Rivas H, Islam A, Soper N, Paraskeva P, Rosemurgy A, Ross S, Shah S. Single-incision laparoscopic cholecystectomy is associated with improved cosmesis scoring at the cost of significantly higher hernia rates: 1-year results of a prospective randomized, multicenter, single-blinded trial of traditional multiport laparoscopic cholecystectomy vs single-incision laparoscopic cholecystectomy. J Am Coll Surg. 2013 Jun;216(6):1037-47; discussion 1047-8. doi: 10.1016/j.jamcollsurg.2013.02.024. Epub 2013 Apr 23. PubMed PMID: 23619321.
  • Phillips MS, Marks JM, Roberts K, Tacchino R, Onders R, DeNoto G, Rivas H, Islam A, Soper N, Gecelter G, Rubach E, Paraskeva P, Shah S. Intermediate results of a prospective randomized controlled trial of traditional four-port laparoscopic cholecystectomy versus single-incision laparoscopic cholecystectomy. Surg Endosc. 2012 May;26(5):1296-303. doi: 10.1007/s00464-011-2028-z. Epub 2011 Nov 15. PubMed PMID: 22083331.
  • Gonzalez-Bermejo J, Morélot-Panzini C, Salachas F, Redolfi S, Straus C, Becquemin MH, Arnulf I, Pradat PF, Bruneteau G, Ignagni AR, Diop M, Onders R, Nelson T, Menegaux F, Meininger V, Similowski T. Diaphragm pacing improves sleep in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2012 Jan;13(1):44-54. doi: 10.3109/17482968.2011.597862. Epub 2011 Oct 24. PubMed PMID: 22023158.
  • Onders RP. Functional electrical stimulation: restoration of respiratory function. Handb Clin Neurol. 2012;109:275-82. doi: 10.1016/B978-0-444-52137-8.00017-6. Review. PubMed PMID: 23098719.

Onders

PROFESSIONAL AFFILIATIONS

Investigator
Cleveland FES Center

Director, Adult Minimally Invasive Surgery
University Hospitals Cleveland Medical Center

Interim Chief, Division of General and Gastrointestinal Surgery
University Hospitals Cleveland Medical Center

Professor, Surgery, School of Medicine
Case Western Reserve University

CONTACT INFORMATION

Program Contact
Ray Onders

Contact Number
(216) 844-5797

Contact Email
Raymond.Onders@UHhospitals.org