I have a broad background in functional neurosurgery, with specific training and expertise in stereotaxy, epilepsy surgery, physiology, and neuromodulation.

My clinical and research interests include movement disorders, epilepsy surgery, and development of novel treatments for a variety of disorders using neuromodulation.

Research Programs

  • Neurostimulation applications
  • Epileptogenic zone identification
  • Neurophysiological changes in brain injury
  • Neural interface technology

Publications (Select)

Entire publication list can be found here.

  • Kumar AMS, Miller J, Hoffer SA, Mansur DB, Coffey M, Lo SS, Sloan AE, Machtay M. Postoperative hypofractionated stereotactic brain radiation (HSRT) for resected brain metastases: improved local control with higher BED10. J Neurooncol. 2018 May 10; doi: 10.1007/s11060-018-2885-6 Pubmed PMID: 29749569
  • Vakharia VN, Sparks R, Rodionov R, Vos SB, Dorfer C, Miller J, Nilsson D, Tisdall M, Wolfsberger S, McEvoy AW, Miserocchi A, Winston GP, O’Keeffe AG, Ourselin S, Duncan JS. Computer-assisted planning for the insertion of stereoelectroencephalography electrodes for the investigation of drug-resistant focal epilepsy: an external validation study. J Neurosurg. 2018 Apr 13;1–10. doi: 10.3171/2017.10.JNS171826 Pubmed PMID: 29652234
  • Young D, Willett F, Memberg WD, Murphy B, Walter B, Sweet J, Miller J, Hochberg LR, Kirsch RF, Ajiboye AB. Signal processing methods for reducing artifacts in microelectrode brain recordings caused by functional electrical stimulation. J Neural Eng. 2018 Apr;15(2):026014. doi: 10.1088/1741-2552/aa9ee8 Pubmed PMID: 29199642
  • Brandman DM, Hosman T, Saab J, Burkhart MC, Shanahan BE, Ciancibello JG, Sarma AA, Milstein DJ, Vargas-Irwin CE, Franco B, Kelemen J, Blabe C, Murphy BA, Young DR, Willett FR, Pandarinath C, Stavisky SD, Kirsch RF, Walter BL, Bolu Ajiboye A, Cash SS, Eskandar EN, Miller JP, Sweet JA, Shenoy KV, Henderson JM, Jarosiewicz B, Harrison MT, Simeral JD, Hochberg LR. Rapid calibration of an intracortical brain-computer interface for people with tetraplegia. J Neural Eng. 2018 Apr;15(2):026007. doi: 10.1088/1741-2552/aa9ee7 Pubmed PMID: 29363625
  • Lacuey N, Hampson JP, Theeranaew W, Zonjy B, Vithala A, Hupp NJ, Loparo KA, Miller JP, Lhatoo SD. Cortical Structures Associated With Human Blood Pressure Control. JAMA Neurol. 2018 Feb 1;75(2):194–202. doi: 10.1001/jamaneurol.2017.3344 Pubmed PMID: 29181526
  • Willett FR, Murphy BA, Young DR, Memberg WD, Blabe CH, Pandarinath C, Franco B, Saab J, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Simeral JD, Jarosiewicz B, Hochberg LR, Kirsch RF, Ajiboye AB. A Comparison of Intention Estimation Methods for Decoder Calibration in Intracortical Brain-Computer Interfaces. IEEE Trans Biomed Eng. 2017 Dec 14; doi: 10.1109/TBME.2017.2783358 Pubmed PMID: 29989927
  • Girgis F, Greil ME, Fastenau PS, Sweet J, Luders H, Miller JP. Resection of Temporal Neocortex During Multiple Hippocampal Transections for Mesial Temporal Lobe Epilepsy Does not Affect Seizure or Memory Outcome. Oper Neurosurg (Hagerstown). 2017 Dec 1;13(6):711–717. doi: 10.1093/ons/opx031 Pubmed PMID: 29186594
  • Xiao R, Miller JA, Lubelski D, Mroz TE, Benzel EC, Krishnaney AA, Machado A. Clinical Outcomes Following Surgical Management of Coexisting Parkinson Disease and Cervical Spondylotic Myelopathy. Neurosurgery. 2017 Aug 1;81(2):350–356. doi: 10.1093/neuros/nyw043 Pubmed PMID: 28327909
  • Kotecha R, Miller JA, Modugula S, Barnett GH, Murphy ES, Reddy CA, Suh JH, Neyman G, Machado A, Nagel S, Chao ST. Stereotactic Radiosurgery for Trigeminal Neuralgia Improves Patient-Reported Quality of Life and Reduces Depression. Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1078–1086. doi: 10.1016/j.ijrobp.2017.04.008 Pubmed PMID: 28721891
  • Willett FR, Murphy BA, Memberg WD, Blabe CH, Pandarinath C, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Hochberg LR, Kirsch RF, Ajiboye AB. Signal-independent noise in intracortical brain-computer interfaces causes movement time properties inconsistent with Fitts’ law. J Neural Eng. 2017 Apr;14(2):026010. doi: 10.1088/1741-2552/aa5990 Pubmed PMID: 28177925
  • Willett FR, Pandarinath C, Jarosiewicz B, Murphy BA, Memberg WD, Blabe CH, Saab J, Walter BL, Sweet JA, Miller JP, Henderson JM, Shenoy KV, Simeral JD, Hochberg LR, Kirsch RF, Ajiboye AB. Feedback control policies employed by people using intracortical brain-computer interfaces. J Neural Eng. 2017 Feb;14(1):016001. doi: 10.1088/1741-2560/14/1/016001 Pubmed PMID: 27900953
  • Cardinale F, Casaceli G, Raneri F, Miller J, Lo Russo G.Implantation of Stereoelectroencephalography Electrodes: A Systematic Review. J Clin Neurophysiol. 2016 Dec;33(6):490-502. Review. PubMed PMID: 27918344
  • Ostergard T, Sweet J, Kusyk D, Herring E, Miller J. Animal models of post-traumatic epilepsy. J Neurosci Methods. 2016 Oct 15;272:50-55. doi: 10.1016/j.jneumeth.2016.03.023. Epub 2016 Apr 1. Review. PubMed PMID: 27044802.
  • Hayek SM, Sweet JA, Miller JP, Sayegh RR. Successful Management of Corneal Neuropathic Pain with Intrathecal Targeted Drug Delivery. Pain Med. 2016 Jul;17(7):1302-7. doi: 10.1093/pm/pnv058. Epub 2015 Dec 14. PubMed PMID: 26814286.
  • Park JT, Manjila SV, Tangen RB, Cohen ML, Shahid AM, Sweet JA, Tuxhorn IE, Miller JP. Tailored disconnection based on presurgical evidence in catastrophic epilepsy: report of 2 cases. J Neurosurg Pediatr. 2016 Jun;17(6):679-82. doi: 10.3171/2015.11.PEDS15495. Epub 2016 Feb 12. PubMed PMID: 26870899.
  • Alonso F, Sweet J, Miller J. Speech mapping using depth electrodes: The “electric Wada”. Clin Neurol Neurosurg. 2016 May;144:88-90. doi: 10.1016/j.clineuro.2016.03.017. Epub 2016 Mar 25. PubMed PMID: 27035743.
  • Koubeissi MZ, Kahriman E, Fastenau P, Bailey C, Syed T, Amina S, Miller J, Munyon C, Tanner A, Karanec K, Tuxhorn I, Lüders H. Multiple hippocampal transections for intractable hippocampal epilepsy: Seizure outcome. Epilepsy Behav. 2016 May;58:86-90. doi: 10.1016/j.yebeh.2016.03.004. Epub 2016 Apr 8. PubMed PMID: 27064827.
  • Sayegh RR, Sweet JA, Miller JP, Hayek SM. Electrical Stimulation of the Trigeminal Ganglion and Intrathecal Drug Delivery Systems for the Management of Corneal Neuropathic Pain. Cornea. 2016 Apr;35(4):576-7. doi: 10.1097/ICO.0000000000000751. PubMed PMID: 26807903.
  • Sweet J, Badjatiya A, Tan D, Miller JParesthesia-Free High-Density Spinal Cord Stimulation for Postlaminectomy Syndrome in a Prescreened Population: A Prospective Case Series. Neuromodulation. 2016 Apr;19(3):260-7. doi: 10.1111/ner.12357. Epub 2015 Oct 20. PubMed PMID: 26481726.
  • Tan D, Tyler D, Sweet J, Miller J. Intensity Modulation: A Novel Approach to Percept Control in Spinal Cord Stimulation.Neuromodulation. 2016 Apr;19(3):254-9. doi: 10.1111/ner.12358. Epub 2015 Oct 19. PubMed PMID: 26479774.
  • Girgis F, Pace J, Sweet J, Miller JP. Hippocampal Neurophysiologic Changes after Mild Traumatic Brain Injury and Potential Neuromodulation Treatment Approaches. Front Syst Neurosci. 2016 Feb 9;10:8. doi: 10.3389/fnsys.2016.00008.  eCollection 2016. Review. PubMed PMID: 26903824; PubMed Central PMCID: PMC4746250.
  • Fastenau PS, Bailey CM, Sweet JA, Munyon CN, Lüders HO, Miller JPReply: The challenges for research on deep brain stimulation and memory. Brain. 2016 Feb;139(Pt 2):e13. doi: 10.1093/brain/awv295. Epub 2015 Oct 22. PubMed PMID: 26493636.
  • Suresh S, Sweet J, Fastenau PS, Lüders H, Landazuri P, Miller JTemporal lobe epilepsy in patients with nonlesional MRI and normal memory: an SEEG study. J Neurosurg. 2015 Dec;123(6):1368-74. doi: 10.3171/2015.1.JNS141811. Epub 2015 Jul 24. PubMed PMID: 26207602.
  • Okoye CC, Patel RB, Hasan S, Podder T, Khouri A, Fabien J, Zhang Y, Dobbins D, Sohn JW, Yuan J, Yao M, Machtay M, Sloan AE, Miller J, Lo SS. Comparison of Ray Tracing and Monte Carlo Calculation Algorithms for Thoracic Spine Lesions Treated With CyberKnife-Based Stereotactic Body Radiation Therapy. Technol Cancer Res Treat. 2016 Feb;15(1):196-202. doi: 10.1177/1533034614568026. Epub 2015 Jan 28. PubMed PMID: 25633137.
  • Duan Y, Sweet J, Munyon C, Miller J. Degree of distal trigeminal nerve atrophy predicts outcome after microvascular decompression for Type 1a trigeminal neuralgia. J Neurosurg. 2015 Dec;123(6):1512-8. doi: 10.3171/2014.12.JNS142086. Epub 2015 Jul 17. PubMed PMID: 26186027.
  • Munyon C, Sweet J, Luders H, Lhatoo S, Miller J. The 3-dimensional grid: a novel approach to stereoelectroencephalography.Neurosurgery. 2015 Mar;11 Suppl 2:127-33; discussion 133-4. doi: 10.1227/NEU.0000000000000649. PubMed PMID: 25599199.
  • Sweet J, Eakin K, Munyon C, Miller J. Improved cognition with theta burst stimulation of the fornix in a rat model of traumatic brain injury. Hippocampus 2014 Dec;24(12):1592-600.
  • Munyon C, Sweet J, Luders H, Lhatoo S, Miller J. The 3-Dimensional Grid: A Novel Approach to Stereoelectroencephalography. Neurosurgery. 2015 Jan 16. [Epub ahead of print] PubMed PMID: 25599199.
  • Miller J, Sweet J, Bailey C, Munyon C, Luders H, Fastenau P. Memory for Complex Figures is enhanced with Theta Burst Deep Brain Stimulation of the Fornix. Brain 2015 (in press).
  • Munyon C, Eakin K, Sweet J, Miller JDecreased bursting and novel object-specific cell firing in the hippocampus after mild traumatic brain injury. Brain Res 2014 Sep 25;1582:220-6.
  • Koubeissi MZ, Kahriman E, Syed TU, Miller J, Durand DM. Low-frequency electrical stimulation of a fiber tract in temporal lobe epilepsy. Ann Neurol. 2013 Aug;74(2):223-31. doi: 10.1002/ana.23915. Epub 2013 Sep 4. PubMed PMID: 23613463.
  • Wu S, Hariprasad K, Lhatoo S, Koubeissi M, Miller J, Luders H. Role of ictal direct current shifts and ictal high frequency oscillations in stereo-electroencephalography analysis of mesial temporal lobe seizures. Epilepsia 2014 May;55(5):690-8.


Associate Director of Clinical Affairs @ University Hospitals
Cleveland FES Center

Director, Functional and Restorative Neurosurgery
University Hospitals Cleveland Medical Center

George R. and Constance P. Lincoln Endowed Chair
University Hospitals Cleveland Medical Center

Associate Professor of Neurological Surgery, School of Medicine
Case Western Reserve University


Program Contact
 Jonathan Miller

Contact Number
(216) 844-3470

Contact Email