{"id":32574,"date":"2020-02-06T19:22:21","date_gmt":"2020-02-06T19:22:21","guid":{"rendered":"https:\/\/fescenter.org\/test\/?page_id=32574"},"modified":"2026-04-13T17:04:02","modified_gmt":"2026-04-13T17:04:02","slug":"brain-connectivity-scs-chronic-pain","status":"publish","type":"page","link":"https:\/\/fescenter.org\/test\/research-and-participants\/clinical-trials\/pain-program\/brain-connectivity-scs-chronic-pain\/","title":{"rendered":"Brain Connectivity Changes with Spinal Cord Stimulation"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<div class=\"trial-page\">\n<section class=\"trial-hero\" aria-label=\"Spinal cord stimulation in the treatment of chronic pain hero\">\n<h2 class=\"trial-hero-title\">Spinal Cord Stimulation in the Treatment of Chronic Pain<\/h2>\n<div class=\"hero-layout\">\n<div class=\"hero-text\">\n<p class=\"trial-intro-lead\">This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function.<\/p>\n<p>Chronic pain is a complex neurological disease that adversely impacts function and quality of life. Brain structure and function are altered when an individual is in the chronic pain state. Furthermore, chronic pain is associated with disruptions in functional brain connectivity.<\/p>\n<p>Spinal cord stimulation (SCS) is a clinically available non-pharmacological therapy that is used in the management of chronic pain. Although SCS is effective for many, there are individuals who do not benefit. Therefore, in order to better understand brain mechanisms that underlie SCS treatment of chronic pain and to develop brain biomarkers of SCS efficacy, the investigators propose to evaluate functional brain changes in response to SCS.<\/p>\n<\/div>\n<div class=\"hero-image\" aria-label=\"Primary image\"><img decoding=\"async\" src=\"https:\/\/fescenter.org\/test\/wp-content\/uploads\/2026\/04\/BrainConnectivityChanges.jpg\" alt=\"Spinal cord stimulation in the treatment of chronic pain study\" \/><\/div>\n<\/div>\n<div class=\"trial-body\">\n<p>This study aims to assess how use of spinal cord stimulation (SCS) for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS\/EEG). The<br \/>\ninvestigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long-term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.<\/p>\n<p>Detailed study information is available at <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05811312\">https:\/\/clinicaltrials.gov\/study\/NCT05811312<\/a>.<\/p>\n<\/div>\n<\/section>\n<section class=\"trial-info\" aria-label=\"For more information\">\n<h3 class=\"trial-section-heading\">For More Information<\/h3>\n<div class=\"trial-info-list\" role=\"list\">\n<p role=\"listitem\"><strong>Program Contact:<\/strong> Cheryl Dudek<\/p>\n<p role=\"listitem\"><strong>Contact Number:<\/strong> (216) 679-3800<\/p>\n<p role=\"listitem\"><strong>Contact Email:<\/strong> <a href=\"mailto:Cheryl.dudek@va.gov\">Cheryl.dudek@va.gov<\/a><\/p>\n<\/div>\n<\/section>\n<section class=\"trial-contact\" aria-label=\"Contact request form\">\n<div class=\"contact-card\">\n<h3 class=\"contact-title\">Contact Request<\/h3>\n<p class=\"contact-subtitle\">If you would like more information about becoming a research volunteer please submit the information below.<\/p>\n<form name=\"vscf_32574\" id=\"vscf\" class=\"vscf-shortcode\" method=\"post\">\r\n\t<div class=\"form-group vscf-name-group\">\r\n\t\t<label for=\"vscf_name\" class=\"vscf-label\">Name <\/label>\r\n\t\t<input type=\"text\" name=\"vscf_name_32574\" id=\"vscf_name\"  class=\"form-control\" placeholder=\"\" value=\"\" minlength=\"2\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-email-group\">\r\n\t\t<label for=\"vscf_email\" class=\"vscf-label\">Email <\/label>\r\n\t\t<input type=\"email\" name=\"vscf_email_32574\" id=\"vscf_email\"  class=\"form-control\" placeholder=\"\" value=\"\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\r\n\t<\/div>\r\n\t\r\n\t\t<div class=\"form-group vscf-subject-group\">\r\n\t\t\t<label for=\"vscf_subject\" class=\"vscf-label\">Subject <\/label>\r\n\t\t\t<input type=\"text\" name=\"vscf_subject_32574\" id=\"vscf_subject\"  class=\"form-control\" placeholder=\"\" value=\"\" minlength=\"2\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\t\r\n\t\t<\/div>\r\n\t\r\n\t\r\n\t\t<div class=\"form-group vscf-display-none\">\r\n\t\t\t<input type=\"hidden\" name=\"vscf_sum_32574\" id=\"vscf_sum\" class=\"form-control\" value=\"1733bed6d95085db2896dc4f3e7503ef\" \/>\r\n\t\t<\/div>\r\n\t\r\n\t<div class=\"form-group vscf-hide\">\r\n\t\t<label for=\"vscf_first_random\">Please ignore this field<\/label>\r\n\t\t<input type=\"text\" name=\"vscf_first_random_32574\" id=\"vscf_first_random\" class=\"form-control\" tabindex=\"-1\" value=\"\" maxlength=\"100\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-hide\">\r\n\t\t<label for=\"vscf_second_random\">Please ignore this field<\/label>\r\n\t\t<input type=\"text\" name=\"vscf_second_random_32574\" id=\"vscf_second_random\" class=\"form-control\" tabindex=\"-1\" value=\"\" maxlength=\"100\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-message-group\">\r\n\t\t<label for=\"vscf_message\" class=\"vscf-label\">Message <\/label>\r\n\t\t<textarea name=\"vscf_message_32574\" id=\"vscf_message\" rows=\"10\"  class=\"form-control\" placeholder=\"\" minlength=\"10\" maxlength=\"10000\" aria-required=\"true\"><\/textarea>\r\n\t\t\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-display-none\">\r\n\t\t<input type=\"hidden\" name=\"vscf_time_32574\" id=\"vscf_time\" class=\"form-control\" value=\"1776376631\" \/>\r\n\t<\/div>\r\n\t\r\n\t\t<div class=\"form-group vscf-privacy-group\">\r\n\t\t\t<input type=\"hidden\" name=\"vscf_privacy_32574\" id=\"vscf_privacy_hidden\" value=\"no\" \/>\r\n\t\t\t<input type=\"checkbox\" name=\"vscf_privacy_32574\" id=\"vscf_privacy\" class=\"custom-control-input\" value=\"yes\"  aria-required=\"true\" \/>\r\n\t\t\t<label for=\"vscf_privacy\">I consent to having this website collect my personal data via this form.<\/label>\r\n\t\t\t\r\n\t\t<\/div>\r\n\t\r\n\t<div class=\"form-group vscf-display-none\">\r\n\t\t<input type=\"hidden\" id=\"vscf_nonce\" name=\"vscf_nonce\" value=\"b13379f8d3\" \/><input type=\"hidden\" name=\"_wp_http_referer\" value=\"\/test\/wp-json\/wp\/v2\/pages\/32574\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-submit-group\">\r\n\t\t<button type=\"submit\" name=\"vscf_send_32574\" id=\"vscf_send\" class=\"btn btn-primary\">Submit<\/button>\r\n\t<\/div>\r\n\t\r\n<\/form>\n<\/div>\n<\/section>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;] Spinal Cord Stimulation in the Treatment of Chronic Pain This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. Chronic pain is a complex neurological disease that adversely impacts function and quality of life. Brain structure and function are altered when [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":20642,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-32574","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/32574","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/comments?post=32574"}],"version-history":[{"count":1,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/32574\/revisions"}],"predecessor-version":[{"id":32582,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/32574\/revisions\/32582"}],"up":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/20642"}],"wp:attachment":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/media?parent=32574"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}