{"id":31801,"date":"2026-03-25T19:14:51","date_gmt":"2026-03-25T19:14:51","guid":{"rendered":"https:\/\/fescenter.org\/test\/?page_id=31801"},"modified":"2026-04-09T15:32:12","modified_gmt":"2026-04-09T15:32:12","slug":"restoration-of-cough","status":"publish","type":"page","link":"https:\/\/fescenter.org\/test\/research-and-participants\/clinical-trials\/spinal-cord-injury-programs\/restoration-of-cough\/","title":{"rendered":"Restoration of Cough"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<div class=\"trial-page\">\n<section class=\"trial-hero\" aria-label=\"Stimulation with wire leads to restore cough hero\">\n<h2 class=\"trial-hero-title\">Stimulation With Wire Leads to Restore Cough<\/h2>\n<div class=\"hero-layout\">\n<div class=\"hero-text\">\n<p class=\"trial-intro-lead\">The goal of this project is to implement an effective, more natural cough using a system that can be independently operated by the user.<\/p>\n<p>The purpose of this clinical trial is to determine if a new minimally invasive method of electrical stimulation of the expiratory muscles is capable of producing an effective cough, on demand.<\/p>\n<\/div>\n<div class=\"hero-image\" aria-label=\"Primary image\"><img decoding=\"async\" style=\"max-width: 100%; height: auto;\" src=\"https:\/\/fescenter.org\/test\/wp-content\/uploads\/2026\/02\/CoughImage_edited.jpg\" alt=\"Stimulation with wire leads to restore cough\" \/><\/div>\n<\/div>\n<div class=\"trial-body\">\n<p>The goal of this project is to implement an effective, more natural cough using a system that can be independently operated by the user. This program is for individuals with a cervical level spinal cord injury and secondary impaired or iniffective cough, due to paralysis of the expiratory muscles. The system can be programmed to provide cough of varying intensity &#8211; to best meet the particular needs of each individual.<\/p>\n<p>Through a minimally invasive surgical procedure, 16 adults with cervical spinal injuries (C8 level or higher), at least 6 months following the date of injury, will receive wire leads placed over the surface of their spinal cords on the lower back to stimulate the expiratory muscles and restore cough.<\/p>\n<div class=\"video-box\" aria-label=\"YouTube video player\"><iframe title=\"Stimulation With Wire Leads to Restore Cough\" src=\"https:\/\/www.youtube.com\/embed\/Z9LFxtckwKU\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/div>\n<p>Detailed study information is available at <a href=\"http:\/\/clinicaltrials.gov\/ct2\/show\/NCT01659541f\">http:\/\/clinicaltrials.gov\/ct2\/show\/NCT01659541f<\/a>.<\/p>\n<\/div>\n<\/section>\n<section class=\"trial-info\" aria-label=\"For more information\">\n<h3 class=\"trial-section-heading\">For More Information<\/h3>\n<div class=\"trial-info-list\" role=\"list\">\n<p role=\"listitem\"><strong>Principal Investigators:<\/strong> Anthony F DiMarco, M.D.<\/p>\n<p role=\"listitem\"><strong>Program Contact:<\/strong> Krzysztof E. Kowalski, PhD<\/p>\n<p role=\"listitem\"><strong>Contact Number:<\/strong> (216) 957-3606<\/p>\n<p role=\"listitem\"><strong>Contact Email:<\/strong> <a href=\"mailto:kek5@case.edu\">kek5@case.edu<\/a><\/p>\n<\/div>\n<\/section>\n<section class=\"trial-contact\" aria-label=\"Contact request form\">\n<div class=\"contact-card\">\n<h3 class=\"contact-title\">Contact Request<\/h3>\n<p class=\"contact-goal\">The goal of this clinical trial is to implement an effective, more natural cough using a system that can be independently operated by the user.<\/p>\n<p class=\"contact-subtitle\">If you would like more information about becoming a research volunteer please submit the information below.<\/p>\n<form name=\"vscf_31801\" id=\"vscf\" class=\"vscf-shortcode\" method=\"post\">\r\n\t<div class=\"form-group vscf-name-group\">\r\n\t\t<label for=\"vscf_name\" class=\"vscf-label\">Name <\/label>\r\n\t\t<input type=\"text\" name=\"vscf_name_31801\" id=\"vscf_name\"  class=\"form-control\" placeholder=\"\" value=\"\" minlength=\"2\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-email-group\">\r\n\t\t<label for=\"vscf_email\" class=\"vscf-label\">Email <\/label>\r\n\t\t<input type=\"email\" name=\"vscf_email_31801\" id=\"vscf_email\"  class=\"form-control\" placeholder=\"\" value=\"\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\r\n\t<\/div>\r\n\t\r\n\t\t<div class=\"form-group vscf-subject-group\">\r\n\t\t\t<label for=\"vscf_subject\" class=\"vscf-label\">Subject <\/label>\r\n\t\t\t<input type=\"text\" name=\"vscf_subject_31801\" id=\"vscf_subject\"  class=\"form-control\" placeholder=\"\" value=\"\" minlength=\"2\" maxlength=\"100\" aria-required=\"true\" \/>\r\n\t\t\t\r\n\t\t<\/div>\r\n\t\r\n\t\r\n\t\t<div class=\"form-group vscf-display-none\">\r\n\t\t\t<input type=\"hidden\" name=\"vscf_sum_31801\" id=\"vscf_sum\" class=\"form-control\" value=\"1733bed6d95085db2896dc4f3e7503ef\" \/>\r\n\t\t<\/div>\r\n\t\r\n\t<div class=\"form-group vscf-hide\">\r\n\t\t<label for=\"vscf_first_random\">Please ignore this field<\/label>\r\n\t\t<input type=\"text\" name=\"vscf_first_random_31801\" id=\"vscf_first_random\" class=\"form-control\" tabindex=\"-1\" value=\"\" maxlength=\"100\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-hide\">\r\n\t\t<label for=\"vscf_second_random\">Please ignore this field<\/label>\r\n\t\t<input type=\"text\" name=\"vscf_second_random_31801\" id=\"vscf_second_random\" class=\"form-control\" tabindex=\"-1\" value=\"\" maxlength=\"100\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-message-group\">\r\n\t\t<label for=\"vscf_message\" class=\"vscf-label\">Message <\/label>\r\n\t\t<textarea name=\"vscf_message_31801\" id=\"vscf_message\" rows=\"10\"  class=\"form-control\" placeholder=\"\" minlength=\"10\" maxlength=\"10000\" aria-required=\"true\"><\/textarea>\r\n\t\t\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-display-none\">\r\n\t\t<input type=\"hidden\" name=\"vscf_time_31801\" id=\"vscf_time\" class=\"form-control\" value=\"1776376627\" \/>\r\n\t<\/div>\r\n\t\r\n\t\t<div class=\"form-group vscf-privacy-group\">\r\n\t\t\t<input type=\"hidden\" name=\"vscf_privacy_31801\" id=\"vscf_privacy_hidden\" value=\"no\" \/>\r\n\t\t\t<input type=\"checkbox\" name=\"vscf_privacy_31801\" id=\"vscf_privacy\" class=\"custom-control-input\" value=\"yes\"  aria-required=\"true\" \/>\r\n\t\t\t<label for=\"vscf_privacy\">I consent to having this website collect my personal data via this form.<\/label>\r\n\t\t\t\r\n\t\t<\/div>\r\n\t\r\n\t<div class=\"form-group vscf-display-none\">\r\n\t\t<input type=\"hidden\" id=\"vscf_nonce\" name=\"vscf_nonce\" value=\"b13379f8d3\" \/><input type=\"hidden\" name=\"_wp_http_referer\" value=\"\/test\/wp-json\/wp\/v2\/pages\/31801\" \/>\r\n\t<\/div>\r\n\t<div class=\"form-group vscf-submit-group\">\r\n\t\t<button type=\"submit\" name=\"vscf_send_31801\" id=\"vscf_send\" class=\"btn btn-primary\">Submit<\/button>\r\n\t<\/div>\r\n\t\r\n<\/form>\n<\/div>\n<\/section>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;] Stimulation With Wire Leads to Restore Cough The goal of this project is to implement an effective, more natural cough using a system that can be independently operated by the user. The purpose of this clinical trial is to determine if a new minimally invasive method of electrical stimulation of the expiratory muscles [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":30983,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-31801","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/31801","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/comments?post=31801"}],"version-history":[{"count":5,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/31801\/revisions"}],"predecessor-version":[{"id":31814,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/31801\/revisions\/31814"}],"up":[{"embeddable":true,"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/pages\/30983"}],"wp:attachment":[{"href":"https:\/\/fescenter.org\/test\/wp-json\/wp\/v2\/media?parent=31801"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}