Spinal Cord Stimulation in the Treatment of Chronic Pain
This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function.
Chronic pain is a complex neurological disease that adversely impacts function and quality of life. Brain structure and function are altered when an individual is in the chronic pain state. Furthermore, chronic pain is associated with disruptions in functional brain connectivity.
Spinal cord stimulation (SCS) is a clinically available non-pharmacological therapy that is used in the management of chronic pain. Although SCS is effective for many, there are individuals who do not benefit. Therefore, in order to better understand brain mechanisms that underlie SCS treatment of chronic pain and to develop brain biomarkers of SCS efficacy, the investigators propose to evaluate functional brain changes in response to SCS.
This study aims to assess how use of spinal cord stimulation (SCS) for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The
investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long-term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.
Detailed study information is available at https://clinicaltrials.gov/study/NCT05811312.
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