Dr. Hess-Dunning’s research interests center around developing multi-functional, locally-responsive neural probes for monitoring and improving brain activity and health through electrophysiology, electrochemical measurements, and drug delivery.

Micro- and nano-fabrication processes are developed to integrate into the probes novel or unconventional materials, such as a mechanically-switchable polymer nanocomposite and graphene-based electrodes, to maximize biocompatibility and device viability.

Publications (Select)

Entire publication list can be found here.

1: Hess-Dunning A, Tyler DJ. A Mechanically-Adaptive Polymer Nanocomposite-Based
Intracortical Probe and Package for Chronic Neural Recording. Micromachines
(Basel). 2018 Nov 8;9(11). pii: E583. doi: 10.3390/mi9110583. PubMed PMID:
30413034; PubMed Central PMCID: PMC6265703.

2: French J, Bardot D, Graczyk E, Hess-Dunning A, Lujan JL, Moynahan M, Tan W,
Triolo R, Zbrzeski A. The need for understanding and engaging the patient as
consumer of products developed by neural engineering. J Neural Eng. 2018
Aug;15(4):040201. doi: 10.1088/1741-2552/aac668. Epub 2018 May 21. PubMed PMID:
29781806; PubMed Central PMCID: PMC6196080.

3: Kim Y, Meade SM, Chen K, Feng H, Rayyan J, Hess-Dunning A, Ereifej ES.
Nano-Architectural Approaches for Improved Intracortical Interface Technologies.
Front Neurosci. 2018 Jul 17;12:456. doi: 10.3389/fnins.2018.00456. eCollection
2018. Review. PubMed PMID: 30065623; PubMed Central PMCID: PMC6056633.

4: Nguyen JK, Park DJ, Skousen JL, Hess-Dunning AE, Tyler DJ, Rowan SJ, Weder C,
Capadona JR. Mechanically-compliant intracortical implants reduce the
neuroinflammatory response. J Neural Eng. 2014 Oct;11(5):056014. doi:
10.1088/1741-2560/11/5/056014. Epub 2014 Aug 15. PubMed PMID: 25125443; PubMed
Central PMCID: PMC4175058.


Cleveland FES Center

Research Assistant, Department of Biomedical Engineering
Case Western Reserve University

Biomedical Engineer,
Louis Stokes Cleveland Medical Center


Program Contact
Allison Hess-Dunning, PhD

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