McIntyre, Cameron, Ph.D.

Research Statement

• Neurology
• Neurosurgery
• Deep brain stimulation
• Movement disorders

Professional Affiliations

• Investigator, Cleveland FES Center
• Associate Professor, Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
• Associate Staff, Department of Biomedical Engineering, Cleveland Clinic Foundation,
  Cleveland, OH
• Adjunct Associate Professor, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH
• Biomedical Engineer, Louis Stokes Cleveland VA Medical Center, Cleveland, OH

Publications (Select)

• Frankemolle AM, Wu J, Noecker AM, Voelcker-Rehage C, Ho JC, Vitek JL, McIntyre CC, Alberts JL. Reversing cognitive-motor impairments in Parkinson's disease patients using a computational modelling approach to deep brain stimulation programming. Brain. 2010 Jan 7. [Epub ahead of print] PubMed PMID: 20061324. 
• McIntyre CC, Frankenmolle AM, Wu J, Noecker AM, Alberts JL. Customizing deep brain stimulation to the patient using computational models. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4228-9. PubMed PMID: 19965023. 
• McIntyre CC, Hahn PJ. Network perspectives on the mechanisms of deep brain stimulation. Neurobiol Dis. 2009 Oct 3. [Epub ahead of print] PubMed PMID: 19804831.
• Luján JL, Noecker AM, Butson CR, Cooper SE, Walter BL, Vitek JL, McIntyre CC.  Automated 3-dimensional brain atlas fitting to microelectrode recordings from deep brain stimulation surgeries. Stereotact Funct Neurosurg. 2009;87(4):229-40.  Epub 2009 Jun 26. PubMed PMID: 19556832. 
• Lempka SF, Miocinovic S, Johnson MD, Vitek JL, McIntyre CC. In vivo impedance  spectroscopy of deep brain stimulation electrodes. J Neural Eng. 2009 Aug;6(4):046001. Epub 2009 Jun 3. PubMed PMID: 19494421. 
• Johnson MD, Vitek JL, McIntyre CC. Pallidal stimulation that improves parkinsonian motor symptoms also modulates neuronal firing patterns in primary motor cortex in the MPTP-treated monkey. Exp Neurol. 2009 Sep;219(1):359-62. Epub 2009 May 4. PubMed PMID: 19409895; PubMed Central PMCID: PMC2730829. 
• Butson CR, McIntyre CC. Current Steering to Control the Volume of Tissue Activated During Deep Brain Stimulation. Brain Stimulat. 2008 Jan;1(1):7-15. PubMed PMID: 19142235; PubMed Central PMCID: PMC2621081. 
• Miocinovic S, Lempka SF, Russo GS, Maks CB, Butson CR, Sakaie KE, Vitek JL, McIntyre CC. Experimental and theoretical characterization of the voltage distribution generated by deep brain stimulation. Exp Neurol. 2009 Mar;216(1):166-76. Epub 2008 Dec 11. PubMed PMID: 19118551; PubMed Central PMCID: PMC2645000. 
• Johnson MD, McIntyre CC. Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation. J Neurophysiol. 2008 Nov;100(5):2549-63. Epub 2008 Sep 3. PubMed PMID: 18768645; PubMed Central PMCID: PMC2585404. 
• Lujan JL, Chaturvedi A, McIntyre CC. Tracking the mechanisms of deep brain stimulation for neuropsychiatric disorders. Front Biosci. 2008 May 1;13:5892-904. Review. PubMed PMID: 18508630. 

Research Programs

• Modeling of Neural Systems
• Electric Field Generated by Deep Brain Stimulation
• Systems-Level Model of Deep Brain Stimulation
• Patient-Specific Models of Deep Brain Stimulation
• Deep Brain Stimulation Interactive Visualization System
• Cortical Closed-Loop Control of Deep Brain Stimulation

Contact Information