Van Acker, Gustaf, MD, PhD

Research Statement

My research interest is in pain management and spasticity control using both implantable and non-invasive electrophysiological methods. My active research areas include:

  • Neuromodulation of dorsal columns for pain management using spinal cord stimulation
  • Non-invasive peripheral nerve block using transcutaneous direct current stimulation, with the goal of treating acute and chronic pain as well as spasticity
Professional Affiliations
  • Investigator, Cleveland FES Center
  • PM&R Resident, Case Western Reserve University/MetroHealth
Publications (Select)
  • Van Acker III GM, Bhadra N, Vrabec T, Chae J, Kilgore KL, Bhadra N Block of motor nerve conduction via transcutaneous application of direct current, Bioelectron. Med. (2018) 1(2), 107–116
  • Amundsen SL, Van Acker III GM, Luchies CW & Cheney PD Muscle synergies obtained from comprehensive mapping of the primary motor cortex forelimb representation using high-frequency, long-duration ICMS, J Neurophysiol. 2017 Jul 1;118(1):455-470. Pubmed PMID: 2844658
  • Vrabec T, Bhadra N, Van Acker GM, Bhadra N, Kilgore KL Continuous direct current nerve block using multi contact high capacitance electrodes, IEEE Trans Neural Syst Rehabil Eng. 2017 Jun;25(6):517-529. Pubmed PMID: 27411224.
  • Van Acker III GM, Luchies CW, Cheney PD. Timing of Cortico-Muscle Transmission During Active Movement. Cereb Cortex. 2016 Aug;26(8):3335-44. doi: 10.1093/cercor/bhv151. PubMed PMID: 26209849.
  • Messamore WG, Van Acker III GM, Hudson HM, Zhang HY, Kovac A, Nazzaro J, Cheney PD. Cortical Effects on Ipsilateral Hindlimb Muscles Revealed with Stimulus-Triggered Averaging of EMG Activity. Cereb Cortex. 2016 Jul;26(7):3036-51. doi: 10.1093/cercor/bhv122. PubMed PMID: 26088970.
  • Messamore WG, Van Acker III GM, Hudson HM, Zhang HY, Kovac A, Nazzaro J, Cheney PD. Cortical Effects on Ipsilateral Hindlimb Muscles Revealed with Stimulus-Triggered Averaging of EMG Activity. Cereb Cortex. 2015 Jun 17. pii: bhv122. [Epub ahead of print] PubMed PMID: 26088970.
  • Van Acker III GM, Amundsen SL, Messamore M, Zhang HY, Luchies CW & Cheney PD. Equilibrium-based movement end-points elicited from primary motor cortex using repetitive microstimulation. J Neurosci. 2014 Nov 19;34(47):15722-34. PMID: 25411500
  • Shahdoost S, Frost S, Van Acker III GM, DeJong S, Dunham C, Barbay S, Nudo RJ & Mohseni P. Towards a miniaturized brain-machine-spinal cord interface (BMSI) for restoration of function after spinal cord injury. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug;2014:486-9. PMID: 25570002
  • Nazzaro JM, Klemp JA, Brooks WM, Cook-Wiens G, Van Acker III GM, Mayo MS, Lyons KE & Cheney PD. Deep Brain Stimulation Lead-Contact Heating During 3T MRI: Single- versus Dual-Channel Pulse Generator Configurations. Int J Neurosci. 2014 Mar;124(3):166-74. PMID: 24000873
  • Van Acker III GM, Amundsen SL, Messamore M, Zhang HY, Hudson HM, Luchies CW, Kovac AL & Cheney PD. Effective stimulus parameters for mapping muscle synergies and associated movements evoked from primary motor cortex. J Neurophysiol. 2013 Sep;110(5):1180-9. PMID: 23741044
  • Cheney PD, Griffin DM & Van Acker III GM. Neural hijacking: Action of high-frequency electrical stimulation on cortical circuits. Neuroscientist. 2013 Oct;19(5):434-41. PMID 22968640
Contact Name: Gustaf Van Acker
Contact Number: (216)778-2895
Contact Email: