Shaikh, Aasef, MD, PhD

shaikh-aasef-webResearch Statement

Aasef Shaikh is a neurologist and neuroscientist from Daroff-Dell’Osso Ocular Motility Laboratory at Cleveland VA Medical Center. His research focuses on the application of control systems engineering to approach complex disorders of the vestibular system, eye movements, head movements, gait and balance. The overarching goal is to discover novel network connections and leverage their influence to modulate the motor circuits artificially for the treatment of intractable neurological conditions. Dr. Shaikh was the recipient of the prestigious American Academy of Neurology Alliance Founders Award and The American Neurological Association Grass Foundation Award in Neuroscience.

Professional Affiliations

  • Investigator, Cleveland FES Center
  • Neurologist and Neuroscientist, Louis Stokes Cleveland VA Medical Center, Cleveland, OH
  • Neurologist, University Hospitals Cleveland Medical Center, Cleveland, OH
  • Assistant Professor, Neurology, School of Medicine, Case Western Reserve University, Cleveland, OH

Publications (Select)

  • Shaikh AG. Abnormal head oscillations in neuro-ophthalmology and neuro-otology. Curr Opin Neurol. 2016 Feb;29(1):94-103. doi: 10.1097/WCO.0000000000000277. PubMed PMID: 26641814; PubMed Central PMCID: PMC4734901.
  • Cooperrider J, Gale JT, Gopalakrishnan R, Chan HH, Wathen C, Park HJ, Baker KB, Shaikh AG, Machado AG. Differential frequency modulation of neural activity in the lateral cerebellar nucleus in failed and successful grasps. Exp Neurol. 2015 Dec 14;277:27-34. doi: 10.1016/j.expneurol.2015.12.007. [Epub ahead of print] PubMed PMID: 26698925.
  • Ghasia FF, Wilmot G, Ahmed A, Shaikh AG. Strabismus and Micro-Opsoclonus in Machado-Joseph Disease. Cerebellum. 2015 Aug 26; doi: 10.1007/s12311-015-0718-0 Pubmed PMID: 26306823
  • Shaikh AG, Ghasia FF. Misdirected horizontal saccades in pan-cerebellar atrophy. J Neurol Sci. 2015 Aug 15;355(1-2):125–130. doi: 10.1016/j.jns.2015.05.042 Pubmed PMID: 26070655
  • Shaikh AG. Translational neurophysiology of Parkinson’s disease: can’t blink on an eye blink. J Neurophysiol. 2015 Jul;114(1):761–762. doi: 10.1152/jn.00430.2015 Pubmed PMID: 26220606
  • Shaikh AG, Wong A, Zee DS, Jinnah HA. Why are voluntary head movements in cervical dystonia slow? Parkinsonism Relat Disord. 2015 Jun;21(6):561–566. doi: 10.1016/j.parkreldis.2015.03.005 Pubmed PMID: 25818535
  • Ghasia FF, Shaikh AG, Jacobs J, Walker MF. Cross-coupled eye movement supports neural origin of pattern strabismus. Invest Ophthalmol Vis Sci. 2015 May;56(5):2855–2866. doi: 10.1167/iovs.15-16371 Pubmed PMID: 26024072
  • Ghasia FF, Shaikh AG. Uncorrected Myopic Refractive Error Increases Microsaccade Amplitude. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2531–2535. doi: 10.1167/iovs.14-15882 Pubmed PMID: 25678690
  • Ghasia FF, Shaikh AG. Experimental tests of hypotheses for microsaccade generation. Exp Brain Res. 2015 Apr;233(4):1089–1095. doi: 10.1007/s00221-014-4188-2 Pubmed PMID: 25563497
  • Ghasia FF, Shaikh AG. Head oscillations in infantile nystagmus syndrome. J AAPOS. 2015 Feb;19(1):38–41. doi: 10.1016/j.jaapos.2014.10.024 Pubmed PMID: 25727585
  • Shaikh AG, Sundararajan S. Angioinvasive aspergillosis of the central nervous system. Can J Neurol Sci. 2015 Jan;42(1):64–65. doi: 10.1017/cjn.2014.120 Pubmed PMID: 25525687
  • Ghasia FF, Shaikh AG. Source of high-frequency oscillations in oblique saccade trajectory. Exp Eye Res. 2014 Apr;121:5–10. doi: 10.1016/j.exer.2014.02.009 Pubmed PMID: 24560678

Contact Information

Contact Name: Aasef Shaikh
Contact Number: (216) 844-3192
Contact Email: Aasef.Shaikh@case.edu