Mei, Lin, PhD

Case Western Reserve University, School of Medicine, Dr Lin MeiResearch Statement

The brain contains billions of nerve cells, or neurons, which receive and integrate signals from the environment, and which govern the body’s responses. Nervous system activity is made possible by synapses, contacts formed either between neurons or between a neuron and a target cell. Synapses are asymmetric structures in which neurotransmitter molecules are released from the presynaptic membrane and activate receptors on the postsynaptic membrane, thus establishing neuronal communication. As such, synapses are fundamental units of neural circuitry and enable complex behaviors. Research in our lab has focused on mechanisms of synapse formation, neurotransmission, and synaptic plasticity. Our studies contribute to a better understanding of these processes and development of potential therapeutic strategies for psychiatric disorders such as schizophrenia, autism, and depression and neurological disorders such as muscular dystrophy, spinal cord injury, and epilepsy.‌ 


Professional Affiliations

  • Investigator, Cleveland FES Center
  • Professor and Chair of Neurosciences, Case Western Reserve University, Cleveland, OH
  • Allen C. Holmes Professor of Neurological Diseases, Case Western Reserve University, Cleveland, OH
  • Director, Cleveland Brain Health Initiative, Cleveland, OH

Publications (Select)


Contact Information

Contact Name: Lin Mei
Contact Number: (216) 368-4928
Contact Email: lin.mei@case.edu