Jurjus, George, MD

Research Interests

  • Psychiatry, mental/behavioral health

Professional Affiliations

  • Investigator, Cleveland FES Center
  • Psychiatrist, Louis Stokes VA Medical Center
  • Associate Professor, Psychiatry, CWRU

Publications (Select)

  • Mohamed S, Johnson GR, Chen P, Hicks PB, Davis LL, Yoon J, Gleason TC, Vertrees JE, Weingart K, Tal I, Scrymgeour A, Lawrence DD, Planeta B, Thase ME, Huang GD, Zisook S; and the VAST-D Investigators, Rao SD, Pilkinton PD, Wilcox JA, Iranmanesh A, Sapra M, Jurjus G, Michalets JP, Aslam M, Beresford T, Anderson KD, Fernando R, Ramaswamy S, Kasckow J, Westermeyer J, Yoon G, D’Souza DC, Larson G, Anderson WG, Klatt M, Fareed A, Thompson SI, Carrera CJ, Williams SS, Juergens TM, Albers LJ, Nasdahl CS, Villarreal G, Winston JL, Nogues CA, Connolly KR, Tapp A, Jones KA, Khatkhate G, Marri S, Suppes T, LaMotte J, Hurley R, Mayeda AR, Niculescu AB 3rd, Fischer BA, Loreck DJ, Rosenlicht N, Lieske S, Finkel MS, Little JT. Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial. JAMA. 2017 Jul 11;318(2):132-145. doi: 10.1001/jama.2017.8036. PubMed PMID: 28697253.
  • Rubinow MJ, Mahajan G, May W, Overholser JC, Jurjus GJ, Dieter L, Herbst N Steffens DC, Miguel-Hidalgo JJ, Rajkowska G, Stockmeier CA. Basolateral amygdala volume and cell numbers in major depressive disorder: a postmortem stereological study. Brain Struct Funct. 2016 Jan;221(1):171-84. doi: 10.1007/s00429-014-0900-z. Epub 2014 Oct 7. PubMed PMID: 25287512; PubMed Central PMCID: PMC4388764.
  • Miguel-Hidalgo JJ, Jiang W, Konick L, Overholser JC, Jurjus GJ, Stockmeier CA, Steffens DC, Krishnan KRR, Rajkowska G. Morphometric analysis of vascular pathology in the orbitofrontal cortex of older subjects with major depression. Int J Geriatr Psychiatry. 2013 Sep;28(9):959–970. doi: 10.1002/gps.3911 Pubmed PMID: 23208772
  • Cobb JA, Simpson J, Mahajan GJ, Overholser JC, Jurjus GJ, Dieter L, Herbst N, May W, Rajkowska G, Stockmeier CA. Hippocampal volume and total cell numbers in major depressive disorder. J Psychiatr Res. 2013 Mar;47(3):299–306. doi: 10.1016/j.jpsychires.2012.10.020 Pubmed PMID: 23201228
  • Duric V, Banasr M, Stockmeier CA, Simen AA, Newton SS, Overholser JC, Jurjus GJ, Dieter L, Duman RS. Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects. Int J Neuropsychopharmacol. 2013 Feb;16(1):69–82. doi: 10.1017/S1461145712000016 Pubmed PMID: 22339950
  • Zhu H, Urban DJ, Blashka J, McPheeters MT, Kroeze WK, Mieczkowski P, Overholser JC, Jurjus GJ, Dieter L, Mahajan GJ, Rajkowska G, Wang Z, Sullivan PF, Stockmeier CA, Roth BL. Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders. PLoS ONE. 2012;7(8):e43227. doi: 10.1371/journal.pone.0043227 Pubmed PMID: 22912834
  • Johnson S, Stockmeier CA, Meyer JH, Austin MC, Albert PR, Wang J, May WL, Rajkowska G, Overholser JC, Jurjus G, Dieter L, Johnson C, Sittman DB, Ou X-M. The reduction of R1, a novel repressor protein for monoamine oxidase A, in major depressive disorder. Neuropsychopharmacology. 2011 Sep;36(10):2139–2148. doi: 10.1038/npp.2011.105 Pubmed PMID: 21654740
  • Miguel-Hidalgo JJ, Overholser JC, Jurjus GJ, Meltzer HY, Dieter L, Konick L, Stockmeier CA, Rajkowska G. Vascular and extravascular immunoreactivity for intercellular adhesion molecule 1 in the orbitofrontal cortex of subjects with major depression: age-dependent changes. J Affect Disord. 2011 Aug;132(3):422–431. doi: 10.1016/j.jad.2011.03.052 Pubmed PMID: 21536333

Contact Information

Contact Name: George Jurjus
Contact Number: (216) 368-6814
Contact Email: george.jurjus@va.gov