Durand, Dominique, PhD

Research Statement

Dr. Durand’s research interests are in neural engineering and include computational neuroscience, neurophysiology and control of epilepsy, non-linear dynamics of neural systems, neural prostheses and applied magnetic and electrical field interactions with neural tissue.


Professional Affiliations

  • Investigator, Cleveland FES Center
  • EL Lindseth Professor of Biomedical Engineering, Case Western Reserve University, Cleveland, OH
  • Departments of Biomedical Engineering, Neurosciences, Physiology and Biophysics, Case Western Reserve University, Cleveland, OH
  • Director, Neural Engineering Center, Case Western Reserve University, Cleveland, OH
  • Editor in chief, Journal of Neural Engineering, Case Western Reserve University, Cleveland, OH



Publications (Select)

  • Qiu C, Shivacharan RS, Zhang M, Durand DM. Can Neural Activity Propagate by Endogenous Electrical Field? J Neurosci. 2015 Dec 2;35(48):15800-11. doi: 10.1523/JNEUROSCI.1045-15.2015. PubMed PMID: 26631463; PubMed Central PMCID: PMC4666910.
  • Park HJ, Durand DM. Motion control of the rabbit ankle joint with a flat interface nerve electrode. Muscle Nerve. 2015 Dec;52(6):1088-95. doi: 10.1002/mus.24654. Epub 2015 Sep 7. PubMed PMID: 25786911; PubMed Central PMCID:  PMC4575232.
  • Dweiri YM, Eggers T, McCallum G, Durand DM. Ultra-low noise miniaturized neural amplifier with hardware averaging. J Neural Eng. 2015 Aug;12(4):046024. doi: 10.1088/1741-2560/12/4/046024. Epub 2015 Jun 17. PubMed PMID: 26083774.
  • Ladas TP, Chiang CC, Gonzalez-Reyes LE, Nowak T, Durand DM. Seizure reduction through interneuron-mediated entrainment using low frequency optical stimulation. Exp Neurol. 2015 Jul;269:120-32. doi: 10.1016/j.expneurol.2015.04.001. Epub 2015 Apr 8. PubMed PMID: 25863022; PubMed Central PMCID: PMC4446206.
  • Chiang CC, Ladas TP, Gonzalez-Reyes LE, Durand DM. Seizure suppression by high frequency optogenetic stimulation using in vitro and in vivo animal models of epilepsy. Brain Stimul. 2014 Nov-Dec;7(6):890-9. doi: 10.1016/j.brs.2014.07.034.  Epub 2014 Jul 19. PubMed PMID: 25108607; PubMed Central PMCID: PMC4259846.
  • Feng Z, Yu Y, Guo Z, Cao J, Durand DM. High frequency stimulation extends the refractory period and generates axonal block in the rat hippocampus. Brain Stimul. 2014 Sep-Oct;7(5):680-9. doi: 10.1016/j.brs.2014.03.011. Epub 2014 Apr 4. PubMed PMID: 24938914; PubMed Central PMCID: PMC4167911.
  • Park HJ, Durand DM. Motion control of the ankle joint with a multiple contact nerve cuff electrode: a simulation study. Biol Cybern. 2014 Aug;108(4):445-57. doi: 10.1007/s00422-014-0612-8. Epub 2014 Jun 18. PubMed PMID: 24939581.
  • Durand DM, Ghovanloo M, Krames E. Time to address the problems at the neural interface. J Neural Eng. 2014 Apr;11(2):020201. doi: 10.1088/1741-2560/11/2/020201. Epub 2014 Feb 6. PubMed PMID: 24503546.
  • Zhang M, Ladas TP, Qiu C, Shivacharan RS, Gonzalez-Reyes LE, Durand DM. Propagation of epileptiform activity can be independent of synaptic transmission, gap junctions, or diffusion and is consistent with electrical field transmission. J Neurosci. 2014 Jan 22;34(4):1409-19. doi: 10.1523/JNEUROSCI.3877-13.2014. PubMed PMID: 24453330; PubMed Central PMCID: PMC3898297.
  • Wang Y, Toprani S, Tang Y, Vrabec T, Durand DM. Mechanism of highly synchronized bilateral hippocampal activity. Exp Neurol. 2014 Jan;251:101-11. doi: 10.1016/j.expneurol.2013.11.014. Epub 2013 Nov 19. PubMed PMID: 24262205; PubMed Central PMCID: PMC3902113.
  • Tang Y, Wodlinger B, Durand DM. An algorithm for source signal extraction from the peripheral nerve. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:4251–4254. doi: 10.1109/IEMBS.2011.6091055 Pubmed PMID: 22255278
  • Lee S, Ryu K, Waldo AL, Khrestian CM, Durand DM, Sahadevan J. An algorithm to measure beat-to-beat cycle lengths for assessment of atrial electrogram rate and regularity during atrial fibrillation. J Cardiovasc Electrophysiol. 2013 Feb;24(2):199–206. doi: 10.1111/jce.12014 Pubmed PMID: 23140386

Contact Information

Contact Name: Dominique Durand
Contact Number: (216) 368-3974
Contact Email: dxd6@case.edu